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1

A Randomized Clinical Trial of Berberine Hydrochloride in Patients with Diarrhea-Predominant Irritable Bowel Syndrome

Chen, Chunqiu, Tao, Chunhua, Liu, Zhongchen, Lu, Meiling, Pan, Qiuhui, Zheng, Lijun, Li, Qing, Song, Zhenshun, Fichna, Jakub

Journal:

Phytotherapy Research

Year:

2015

Language:

english

File:

PDF, 665 KB

english, 2015

2

Cannabinoids as gastrointestinal anti-inflammatory drugs

Fabisiak, A., Fichna, J.

Journal:

Neurogastroenterology & Motility

Year:

2017

Language:

english

File:

PDF, 421 KB

english, 2017

3

Targeting Histamine Receptors in Irritable Bowel Syndrome: A Critical Appraisal

Fabisiak, Adam, Włodarczyk, Jakub, Fabisiak, Natalia, Storr, Martin, Fichna, Jakub

Journal:

Journal of Neurogastroenterology and Motility

Year:

2017

Language:

english

File:

PDF, 542 KB

english, 2017

4

Polyphenols as mitochondria-targeted anticancer drugs

Gorlach, Sylwia, Fichna, Jakub, Lewandowska, Urszula

Journal:

Year:

2015

Language:

english

File:

PDF, 314 KB

english, 2015

5

Neuropharmacological characterization of the oneirogenic Mexican plantCalea zacatechichiaqueous extract in mice

Sałaga, Maciej, Fichna, Jakub, Socała, Katarzyna, Nieoczym, Dorota, Pieróg, Mateusz, Zielińska, Marta, Kowalczuk, Anna, Wlaź, Piotr

Journal:

Metabolic Brain Disease

Year:

2016

Language:

english

File:

PDF, 678 KB

english, 2016

6

Recent advances in the pharmacological management of constipation predominant irritable bowel syndrome

Niewinna, Karolina, Zielińska, Anna, Fichna, Jakub

Journal:

Expert Opinion on Pharmacotherapy

Year:

2019

Language:

english

File:

PDF, 1.24 MB

english, 2019

7

Non-Classic Disorder of Adrenal Steroidogenesis and Clinical Dilemmas in 21-Hydroxylase Deficiency Combined with Backdoor Androgen Pathway. Mini-Review and Case Report

SumiÅska, Marta, Bogusz-GÃ³rna, Klaudia, Wegner, Dominika, Fichna, Marta

Journal:

International Journal of Molecular Sciences

Year:

2020

File:

PDF, 539 KB

2020

8

Novel highly potent μ-opioid receptor antagonist based on endomorphin-2 structure

Jakub Fichna, Jean-Claude do-Rego, Tomasz Janecki, Renata Staniszewska, Jeroen Poels, Jozef Vanden Broeck, Jean Costentin, Peter W. Schiller, Anna Janecka

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 136 KB

english, 2008

9

Screening for associated autoimmune disorders in Polish patients with Addison’s disease

Marta Fichna, Piotr Fichna, Maria Gryczyńska, Jarosław Walkowiak, Magdalena Żurawek, Jerzy Sowiński

Journal:

Endocrine (Springer)

Year:

2010

Language:

english

File:

PDF, 334 KB

english, 2010

10

Effects of Berberine in the Gastrointestinal Tract — A Review of Actions and Therapeutic Implications

Chen, Chunqiu, Yu, Zhen, Li, Yongyu, Fichna, Jakub, Storr, Martin

Journal:

The American Journal of Chinese Medicine

Year:

2014

Language:

english

File:

PDF, 285 KB

english, 2014

11

Determination of 21-hydroxylase autoantibodies: inter-laboratory concordance in the Euradrenal International Serum Exchange Program

Falorni, Alberto, Bini, Vittorio, Betterle, Corrado, Brozzetti, Annalisa, Castaño, Luis, Fichna, Marta, Kämpe, Olle, Mellgren, Gunnar, Peterson, Pärt, Chen, Shu, Rönnelid, Johan, Seissler, Jochen, Tib

Journal:

Clinical Chemistry and Laboratory Medicine

Year:

2015

Language:

english

File:

PDF, 521 KB

english, 2015

12

Fat-soluble Vitamin Deficiencies and Inflammatory Bowel Disease

Fabisiak, Natalia, Fabisiak, Adam, Watala, Cezary, Fichna, Jakub

Journal:

Journal of Clinical Gastroenterology

Year:

2017

Language:

english

File:

PDF, 513 KB

english, 2017

13

Novel derivatives of 1,2,3-triazole, cannabinoid-1 receptor ligands modulate gastrointestinal motility in mice

Szymaszkiewicz, Agata, Zielinska, Marta, Li, Kun, Ramanathan, Mani, Alam, Safiul, Hou, Duen-Ren, Fichna, Jakub, Storr, Martin

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

2018

Language:

english

File:

PDF, 1.08 MB

english, 2018

14

Alanine scan of sialorphin and its hybrids with opiorphin: synthesis, molecular modelling and effect on enkephalins degradation

Sobocińska, Małgorzata, Giełdoń, Artur, Fichna, Jakub, Kamysz, Elżbieta

Journal:

Year:

2018

Language:

english

File:

PDF, 910 KB

english, 2018

15

Whole-exome sequencing identifies novel pathogenic mutations and putative phenotype-influencing variants in Polish limb-girdle muscular dystrophy patients

Fichna, Jakub Piotr, Macias, Anna, Piechota, Marcin, Korostyński, Michał, Potulska-Chromik, Anna, Redowicz, Maria Jolanta, Zekanowski, Cezary

Journal:

Year:

2018

Language:

english

File:

PDF, 1.06 MB

english, 2018

16

The novel peripherally active cannabinoid type 1 and serotonin type 3 receptor agonist AM9405 inhibits gastrointestinal motility and reduces abdominal pain in mouse models mimicking irritable bowel syndrome

Salaga, Maciej, Binienda, Agata, Tichkule, Ritesh B., Thakur, Ganesh A., Makriyannis, Alexandros, Storr, Martin, Fichna, Jakub

Journal:

European Journal of Pharmacology

Year:

2018

Language:

english

File:

PDF, 889 KB

english, 2018

17

[IEEE 2018 IEEE Nuclear & Space Radiation Effects Conference (NSREC 2018) - Waikoloa, HI, USA (2018.7.16-2018.7.20)] 2018 IEEE Nuclear & Space Radiation Effects Conference (NSREC 2018) - SEL/SEU/SEFI/TID Results of the Radiation Hardened DDR3 SDRAM Memory Solution

Wang, Pierre-Xiao, Kohler, Pierre, Herrmann, Martin, Fichna, Torsten, Pouget, Vincent, Saigne, Frederic

Year:

2018

Language:

english

File:

PDF, 690 KB

english, 2018

18

Corrigendum to “The novel peripherally active cannabinoid type 1 and serotonin type 3 receptor agonist AM9405 inhibits gastrointestinal motility and reduces abdominal pain in mouse models mimicking irritable bowel syndrome” [Eur. J. Pharmacol. (2018), 836 34–43]

Salaga, Maciej, Binienda, Agata, Tichkule, Ritesh B., Thakur, Ganesh A., Makriyannis, Alexandros, Storr, Martin, Fichna, Jakub

Journal:

European Journal of Pharmacology

Year:

2019

File:

PDF, 136 KB

2019

19

Genetic Molecular Subtypes in Optimizing Personalized Therapy for Metastatic Colorectal Cancer

Włodarczyk, Marcin, Włodarczyk, Jakub, Siwiński, Paweł, Sobolewska-Włodarczyk, Aleksandra, Fichna, Jakub

Journal:

Current Drug Targets

Year:

2018

File:

PDF, 816 KB

2018

20

Opioids in Cancer Development, Progression and Metastasis: Focus on Colorectal Cancer

Szczepaniak, Adrian, Fichna, Jakub, Zielińska, Marta

Journal:

Current Treatment Options in Oncology

Year:

2020

Language:

english

File:

PDF, 564 KB

english, 2020

21

Silver nanoparticles based on blackcurrant extract show potent anti-inflammatory effect in vitro and in DSS-induced colitis in mice

Krajewska, Julia B., DÅugosz, Olga, SaÅaga, Maciej, Banach, Marcin, Fichna, Jakub

Journal:

International Journal of Pharmaceutics

Year:

2020

File:

PDF, 479 KB

2020

22

Traditional Chinese Medicine Da-Cheng-Qi-Tang Ameliorates Impaired Gastrointestinal Motility and Intestinal Inflammatory Response in a Mouse Model of Postoperative Ileus

Chen, Chunqiu, Li, Min, Liu, Xiaohong, Fan, Jianwei, Zhang, Hong, Lin, Sisi, Yin, Lu, Fichna, Jakub, Li, Yongyu

Journal:

Evidence-based Complementary and Alternative Medicine

Year:

2020

File:

PDF, 6.53 MB

2020

23

Synthesis and biological activity of N-methylated analogs of endomorphin-2

Rafal Kruszynski, Jakub Fichna, Jean-Claude do-Rego, Tomasz Janecki, Piotr Kosson, Wanda Pakulska, Jean Costentin, Anna Janecka

Journal:

Bioorganic & Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 170 KB

english, 2005

24

Biological activity of endomorphin and [Dmt1]endomorphin analogs with six-membered proline surrogates in position 2

Renata Perlikowska, Katarzyna Gach, Jakub Fichna, Geza Toth, Bogdan Walkowiak, Jean-Claude do-Rego, Anna Janecka

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 302 KB

english, 2009

25

Synthesis and opioid activity of novel 6-substituted-6-demethoxy-ethenomorphinans

Barbara Czakó, János Marton, Sándor Berényi, Katarzyna Gach, Jakub Fichna, Martin Storr, Géza Tóth, Attila Sipos, Anna Janecka

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 597 KB

english, 2010

26

Synthesis and biological evaluation of new salvinorin A analogues incorporating natural amino acids

Jakub Fichna, Kevin Lewellyn, Feng Yan, Bryan L. Roth, Jordan K. Zjawiony

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 258 KB

english, 2011

27

Microcalorimeter array for the measurement of kinetic energies of small particles in space

M. Kobusch, S. Sarge, K.D. Bunte, T. Fichna, D. Hagedorn, F. Jäger, R. Meeß

Journal:

Thermochimica Acta

Year:

2009

Language:

english

File:

PDF, 1.26 MB

english, 2009

28

Deletion mapping of interval 6 of the human Y chromosome

Maciej Kotecki, Jadwiga Jaruzelska, Malgorzata Skowrońska, Piotr Fichna

Journal:

Year:

1991

Language:

english

File:

PDF, 268 KB

english, 1991

29

Effects of duration of gonadectomy, sex and age on adrenal steroid 5α-reductase activity in the rat

L. K. Malendowicz, P. Fichna

Journal:

Cellular and Molecular Life Sciences

Year:

1981

Language:

english

File:

PDF, 226 KB

english, 1981

30

Rapid increase in the incidence of type 1 diabetes in Polish children from 1989 to 2004, and predictions for 2010 to 2025

P. Jarosz-Chobot, J. Polanska, A. Szadkowska, A. Kretowski, E. Bandurska-Stankiewicz, M. Ciechanowska, G. Deja, M. Mysliwiec, J. Peczynska, J. Rutkowska, A. Sobel-Maruniak, P. Fichna, A. Chobot, M. Re

Journal:

Year:

2011

Language:

english

File:

PDF, 284 KB

english, 2011

31

The role of morphine in regulation of cancer cell growth

Katarzyna Gach, Anna Wyrębska, Jakub Fichna, Anna Janecka

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

2011

Language:

english

File:

PDF, 255 KB

english, 2011

32

Normal-range albuminuria does not exclude nephropathy in diabetic children

Jacek Zachwieja, Jolanta Soltysiak, Piotr Fichna, Katarzyna Lipkowska, Witold Stankiewicz, Bogda Skowronska, Pawel Kroll, Maria Lewandowska-Stachowiak

Journal:

Pediatric Nephrology

Year:

2010

Language:

english

File:

PDF, 324 KB

english, 2010

33

Erratum to: Normal-range albuminuria does not exclude nephropathy in diabetic children

Jacek Zachwieja, Jolanta Soltysiak, Piotr Fichna, Katarzyna Lipkowska, Witold Stankiewicz, Bogda Skowronska, Pawel Kroll, Maria Lewandowska-Stachowiak

Journal:

Pediatric Nephrology

Year:

2010

Language:

english

File:

PDF, 48 KB

english, 2010

34

Polymorphisms in 5′-flanking regions of genes encoding adiponectin, leptin, and resistin are not associated with obesity of Polish children and adolescents

Jakub Cieslak, Anna Skorczyk, Monika Stachowiak, Maciej Szydlowski, Maria Grzes, Paulina Paczynska, Bogda Skowronska, Katarzyna Majewska, Witold Stankiewicz, Piotr Fichna, Marek Switonski

Journal:

Molecular Biology Reports

Year:

2011

Language:

english

File:

PDF, 168 KB

english, 2011

35

Effect of three common SNPs in 5′-flanking region ofLEPandADIPOQgenes on their expression in Polish obese children and adolescents

J. Cieslak, M. Bartz, M. Stachowiak, B. Skowronska, K. A. Majewska, J. Harasymczuk, W. Stankiewicz, P. Fichna, M. Switonski

Journal:

Molecular Biology Reports

Year:

2012

Language:

english

File:

PDF, 194 KB

english, 2012

36

Missense mutations and polymorphisms of theMC4Rgene in Polish obese children and adolescents in relation to the relative body mass index

Joanna Nowacka-Woszuk, Jakub Cieslak, Bogda Skowronska, Katarzyna A. Majewska, Witold Stankiewicz, Piotr Fichna, Marek Switonski

Journal:

Journal of Applied Genetics

Year:

2011

Language:

english

File:

PDF, 135 KB

english, 2011

37

Synthesis of novel morphiceptin analogues modified in position 3 and their binding to μ-opioid receptors in experimental mammary adenocarcinoma

A Janecka, J Fichna, R Wiercioch, M Mirowski

Journal:

Bioorganic & Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 282 KB

english, 2003

38

The tryptophan 620 allele of the lymphoid tyrosine phosphatase (PTPN22) gene predisposes to autoimmune Addison's disease

Matthew Roycroft, Marta Fichna, David McDonald, Kate Owen, Magdalena Żurawek, Maria Gryczyńska, Danuta Januszkiewicz-Lewandowska, Piotr Fichna, Heather Cordell, Peter Donaldson, Jerzy Nowak, Simon Pea

Journal:

Clinical Endocrinology

Year:

2009

Language:

english

File:

PDF, 144 KB

english, 2009

39

Salvinorin A inhibits colonic transit and neurogenic ion transport in mice by activating κ-opioid and cannabinoid receptors

J. Fichna, R. Schicho, C. N. Andrews, M. Bashashati, M. Klompus, D. M. Mckay, K. A. Sharkey, J. K. Zjawiony, A. Janecka, M. A. Storr

Journal:

Neurogastroenterology & Motility

Year:

2009

Language:

english

File:

PDF, 762 KB

english, 2009

40

Differential effects of salvinorin A on endotoxin-induced hypermotility and neurogenic ion transport in mouse ileum

J. Fichna, M. Dicay, S. A. Hirota, D. Traboulsi, J. A. MacDonald, A. Janecka, P. L. Beck, J. K. Zjawiony, W. K. MacNaughton, M. A. Storr

Journal:

Neurogastroenterology & Motility

Year:

2011

Language:

english

File:

PDF, 415 KB

english, 2011

41

Effect of GABA-ergic mechanisms on synaptosomal NO synthesis and the nitrergic component of NANC relaxation in rat ileum

M. Kurjak, J. Fichna, J. Harbarth, A. Sennefelder, H. D. Allescher, V. Schusdziarra, M. Storr, B. Otto

Journal:

Neurogastroenterology & Motility

Year:

2011

Language:

english

File:

PDF, 474 KB

english, 2011

42

HLA class IIDRB, DQA1 and DQB1 polymorphisms in the Polish population from Wielkopolska

M. Jungerman, A. Sanchez-Mazas, P. Fichna, R. Lvanova, D. Charron, J. Hors, S. Djoulah

Journal:

Tissue Antigens

Year:

1997

Language:

english

File:

PDF, 404 KB

english, 1997

43

Binding of endomorphin-2 to μ-opioid receptors in experimental mouse mammary adenocarcinoma

J. Fichna, J.-C. Do-Rego, M. Mirowski, J. Costentin, A. Janecka

Journal:

Chemical Biology & Drug Design

Year:

2005

Language:

english

File:

PDF, 121 KB

english, 2005

44

Novel endomorphin-2 analogs with μ-opioid receptor antagonist activity

R. Kruszynski, J. Fichna, J.-C. Do-Rego, N.N. Chung, P.W. Schiller, P. Kosson, J. Costentin, A. Janecka

Journal:

Chemical Biology & Drug Design

Year:

2005

Language:

english

File:

PDF, 132 KB

english, 2005

45

Design, Synthesis and Pharmacological Characterization of Endomorphin Analogues with Non-Cyclic Amino Acid Residues in Position 2

Renata Perlikowska, Jakub Fichna, Anna Wyrębska, Jeroen Poels, Jozef Vanden Broeck, Geza Toth, Martin Storr, Jean-Claude Do Rego, Anna Janecka

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2010

Language:

english

File:

PDF, 291 KB

english, 2010

46

Characterization of Tachykinin-related Peptides from Different Insect Species on Drosophila Tachykinin Receptor-expressing Cell Line

Jakub Fichna, Jeroen Poels, Jozef Vanden Broeck, Anna Janecka

Journal:

Chemical Biology & Drug Design

Year:

2006

Language:

english

File:

PDF, 113 KB

english, 2006

47

In vitro Characterization of Novel Peptide Inhibitors of Endomorphin-degrading Enzymes in the Rat Brain

Jakub Fichna, Anna Janecka, Laetitia Bailly, Francis Marsais, Jean Costentin, Jean-Claude do Rego

Journal:

Chemical Biology & Drug Design

Year:

2006

Language:

english

File:

PDF, 44 KB

english, 2006

48

μ-Opioid Receptor Ligands Lack Receptor Subtype Selectivity in the Aequorin Luminescence-based Calcium Assay

Jakub Fichna, Renata Staniszewska, Jeroen Poels, Jozef Vanden Broeck, Anna Janecka

Journal:

Chemical Biology & Drug Design

Year:

2007

Language:

english

File:

PDF, 233 KB

english, 2007

49

Synthesis and Biological Activity of Endomorphin-2 Analogs Incorporating Piperidine-2-, 3- or 4-Carboxylic Acids Instead of Proline in Position 2

Renata Staniszewska, Jakub Fichna, Katarzyna Gach, Geza Toth, Jeroen Poels, Jozef Vanden Broeck, Anna Janecka

Journal:

Chemical Biology & Drug Design

Year:

2008

Language:

english

File:

PDF, 85 KB

english, 2008

50

Identification of Endomorphin-1 and Endomorphin-2 Binding Sites in Human μ-Opioid Receptor by Antisense Oligonucleotide Strategy

Jakub Fichna, Katarzyna Gach, Renata Perlikowska, Jeroen Poels, Jozef Vanden Broeck, Janusz Szemraj, Anna Janecka

Journal:

Chemical Biology & Drug Design

Year:

2008

Language:

english

File:

PDF, 288 KB

english, 2008